All aspects of this outer and inner material world were not created by gods, were not made by a doer, have not occurred naturally, have not occurred without a cause, and are not changed by time. They only occur through the characteristics of the root and contributing circumstances of interdependent relative truth. Cause depends on result. Result depends on cause. Not occurring independently, whenever root and contributing circumstances join together, then there is a result. If root and contributing circumstances do not join, then nothing occurs. It is impossible for root circumstances to be obstructed. They only depend on the arising of contributing circumstances. So, when the passions and karma and their suffering are all transcended, including one’s own skandhas without anything remaining, then one attains the space of enlightenment.

— Rongzom Chökyi Zangpo